Newly discovered CRISPR System targets RNA not DNA

MIT News, 2 June 2016, http://news.mit.edu/2016/new-crispr-system-targeting-rna-0602

Feng Zhang’s lab at the Broad Institute has identified a new CRISPR system that targets RNA instead of DNA.  The results, published in Science, (http://science.sciencemag.org/content/early/2016/06/01/science.aaf5573) demonstrate that C2c2 is a programmable single RNA-guided endonuclease that degrades complementary RNA strands with potential uses in knockdown studies similar to RNAi.  The researchers believe that this system could be harnessed to add modules to specific RNAs and be used to track RNA to a subcellular location.

Author: Advanced Analytical

Advanced Analytical Technologies, Inc. (AATI) simplifies complex genomics workflows to accelerate research and discovery in pharmaceuticals, life science, biofuels, biotechnology and healthcare.

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