Induced Pluripotent Stem Cells Used to Study Chlamydia Pathogenesis

Yeung, A.T.Y., et. al. (2017) Nature Communications 8:15013. https://www.ncbi.nlm.nih.gov/pubmed/28440293

Chlamydia is a leading sexually transmitted disease and cause of preventable blindness. Cell based systems to study the interactions between Chlamydia and human macrophages remain limited.  Yeung et al. have developed human induced pluripotent stem cell-derived macrophages that are readily modifiable using CRISPR/Cas9 to study the interactions between Chlamydia and human macrophages.

Author: Advanced Analytical

Advanced Analytical Technologies, Inc. (AATI) simplifies complex genomics workflows to accelerate research and discovery in pharmaceuticals, life science, biofuels, biotechnology and healthcare.

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