David Cyranoski, Nature News, 15 November 2016, http://www.nature.com/news/crispr-gene-editing-tested-in-a-person-for-the-first-time-1.20988
A group at Sichuan University has injected CRISPR edited cells into a patient with aggressive lung cancer. The edited cells contain a disabled PD-1 gene which acts to slow down a cell’s immune response. The theory is that the edited cells will be able to seek out and destroy the cancer cells. A total of 10 patients are planned to participate in this clinical trial with each receiving two, three, or four injections with each patient monitored for six months to determine the safety of the treatment.