Emily Mullin, MIT Technology Review, 17 Jan 2018, https://www.technologyreview.com/s/609999/us-doctors-plan-to-treat-cancer-patients-using-crispr/
The first human CRISPR trials are set to start anytime at the University of Pennsylvania, where doctors will modify human immune cells to target cancer. The first study will have a maximum of 18 patients with multiple myeloma, sarcoma, or melanoma. This type of ex vivo editing followed by injection of the modified cells should prevent the potential immune responses reported on earlier. Additional trials are scheduled to begin later this year in Europe.