Editing of human induced pluripotent stem cells with CRISPR/Cas9 has fundamentally altered the approach to biomedical research

Hockemeyer D., et. al. (2016) Cell Stem Cell.  5:573-586. https://www.ncbi.nlm.nih.gov/pubmed/27152442

The use of human induced pluripotent stem cells(hiPSCs) has allowed researchers to study a variety of diseases and gene functions in non-cancerous cell lines. However the ability to alter the genetics of these cells has posed a significant challenge. With the advent of CRISPR/Cas9 gene editing, modification of hiPSCs has become almost routine.  The combination of these two technologies has changed how researchers study human genetics in a way that will fundamentally alter how scientists approach biomedical research.

Author: Advanced Analytical

Advanced Analytical Technologies, Inc. (AATI) simplifies complex genomics workflows to accelerate research and discovery in pharmaceuticals, life science, biofuels, biotechnology and healthcare.

Leave a Reply