CRISPR/Cas9 edited mushroom will not be regulated by USDA

Emily Waltz, 14 April 2016, Nature News, http://www.nature.com/news/gene-edited-crispr-mushroom-escapes-us-regulation-1.19754

Researchers at Pennsylvania State University have used CRISPR/Cas9 to knock out one of six polyphenol oxidase genes in the common white mushroom.  Polyphenol oxidases are a class of enzymes that cause browning in cut mushrooms.  By knocking out one polyphenol oxidase gene researchers were able to decrease the total polyphenol oxidase activity by approximately 30%, prolonging the shelf life of the mushroom.  Since this mushroom does not contain a transgene, the USDA has ruled that it does not fall under its regulations for genetically modified organisms.

Author: Advanced Analytical

Advanced Analytical Technologies, Inc. (AATI) simplifies complex genomics workflows to accelerate research and discovery in pharmaceuticals, life science, biofuels, biotechnology and healthcare.

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