CRISPR/Cas9 could revolutionize agricultural crop development

Holger Puchta (2017) Current Opinion in Plant Biology 36:1-8. https://www.ncbi.nlm.nih.gov/pubmed/27914284

While zinc finger nucleases and TALENs have both been used to edit plant genomics, the complex nature and high off target effects of these systems has prevented their extensive use.  The ability to use CRISPR for DNA-free gene editing opened the door to the modification of regulatory elements and complex genome rearrangements.  This perspective does not examine the state of the field but looks forward to potential CRISPR applications.

Author: Advanced Analytical

Advanced Analytical Technologies, Inc. (AATI) simplifies complex genomics workflows to accelerate research and discovery in pharmaceuticals, life science, biofuels, biotechnology and healthcare.

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