CRISPR could fix blindness-causing mutation

Alexandra Ossole, Popular Science, 28 January 2016

Retinitis pigmentosa is an inherited disease that causes retina degradation, ultimately resulting in blindness.  This disease has been well characterized, 90% of retinitis pigmentosa cases are the result of a single mutation in a single gene.  Using skin cells from patients with this mutation, researchers were able to generate induced pluripotent stems cells and use CRISPR to correct the mutation.  Researchers hope that these cells may one day be able to be grafted into a patient’s eye to restore sight, or at least slow the progression of the disease.

Author: Advanced Analytical

Advanced Analytical Technologies, Inc. (AATI) simplifies complex genomics workflows to accelerate research and discovery in pharmaceuticals, life science, biofuels, biotechnology and healthcare.

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