CRISPR could be harnessed to eliminate latent herpes viruses

Colin Barras, The New Scientist, 30 June 2016 https://www.newscientist.com/article/2095716-gene-editing-could-destroy-herpes-viruses-living-inside-you/

Most people carry some form of herpes virus, and while most are only revealed by cold sores, the virus can cause blindness, birth defects, cancer, and shingles.  Completely eliminating the viruses from an infected host has proven challenging due to its ability to lay dormant.  However gene editing may allow for the blocking of enzymes responsible for Herpes DNA replication, thus effectively destroying the latent viral population.  Currently this technique has been tried in monkey and human cell lines with up to 95% of the viral population being destroyed; however more research is needed before translation to humans.

Author: Advanced Analytical

Advanced Analytical Technologies, Inc. (AATI) simplifies complex genomics workflows to accelerate research and discovery in pharmaceuticals, life science, biofuels, biotechnology and healthcare.

Leave a Reply