GEN News Highlights, 27 Nov 2017, https://www.genengnews.com/gen-news-highlights/crisprcas-used-to-create-microscopic-data-recorder/81255201
Scientists have created a CRISPR/Cas system in E. coli that allows for the recording of events and the time at which they occurred. This was done by having the cell insert CRISPR spacers at regular occurring sets of time, however when a signal was detected the bacteria would insert a signal sequence instead. This locus can then be read using pre-existing sequencing tools providing a readout of events. The researchers hope this technology could be used to record biological events.