CRISPR Based Methods for Annotation of Regulatory DNA

Klann TS, et. al. (2018) Current Opinion in Biotechnology. 52:32-41. https://www.ncbi.nlm.nih.gov/pubmed/29500989

High-throughput screens for coding regions of the genome have long relied on RNAi technology, but techniques for screening the non-coding regions have not existed until recently.  This review covers how CRISPR technology can be harnessed for annotation of the non-coding regions through genomic and epigenomic screens.

Author: Advanced Analytical

Advanced Analytical Technologies, Inc. (AATI) simplifies complex genomics workflows to accelerate research and discovery in pharmaceuticals, life science, biofuels, biotechnology and healthcare.

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