Automating Cellular Extraction from Live Zebrafish

Lambert, CJ., et. al. (2018) PLoS One 13:e0193180.

Zebrafish have long been a valuable model system with CRISPR gene editing providing even greater opportunities.  One of the major bottlenecks in gene editing is the identification of modified larvae and embryos.  Lambert et. al. developed a zebrafish embryonic genotyping device coined ZEG that uses microfluidic harmonic oscillation of the fish on a glass surface to obtain tissue suitable for genetic analysis.  The researchers determined that this process does not affect body morphology, development, or motor behavior tests.

Author: Advanced Analytical

Advanced Analytical Technologies, Inc. (AATI) simplifies complex genomics workflows to accelerate research and discovery in pharmaceuticals, life science, biofuels, biotechnology and healthcare.

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