Lambert, CJ., et. al. (2018) PLoS One 13:e0193180. https://www.ncbi.nlm.nih.gov/pubmed/29543903
Zebrafish have long been a valuable model system with CRISPR gene editing providing even greater opportunities. One of the major bottlenecks in gene editing is the identification of modified larvae and embryos. Lambert et. al. developed a zebrafish embryonic genotyping device coined ZEG that uses microfluidic harmonic oscillation of the fish on a glass surface to obtain tissue suitable for genetic analysis. The researchers determined that this process does not affect body morphology, development, or motor behavior tests.