Carl Zimmer, The New York Times, 16 Nov 2017. https://www.nytimes.com/2017/11/16/science/gene-drives-crispr.html
Kevin Esvelt of Harvard University was one of the first to put forth the idea of using gene drives to save endangered wildlife from extinction by reducing/eliminating invasive animals. Now Dr. Esvelt has published a new article on bioRxiv in which he presents mathematical models that describe what could happen after the release of a gene drive, even for field trials. These models detail what Dr. Esvelt is calling an unacceptable risk of the altered genes spreading to locations where the targeted species is not invasive. The authors were careful to emphasize that disease eliminating gene drives, such as those proposed to eliminate malaria, should still be considered as this would allow the rapid elimination of disease carrying vectors across wide areas.